Duncan S Holmes Selected Research

GSK180

2/2016

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.

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Duncan S Holmes Research Topics

Disease

5	Netherton Syndrome 01/2021 - 01/2019
3	Allergic Rhinitis 11/2017 - 04/2011
2	Rhinitis 11/2017 - 05/2017
2	Pancreatitis 01/2017 - 01/2017
2	Relapsing-Remitting Multiple Sclerosis 02/2016 - 10/2011
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021
1	Neoplasms (Cancer) 01/2020
1	Amyloid Plaque 01/2020
1	Pain (Aches) 10/2019
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017
1	Huntington Disease (Huntington's Disease) 01/2017
1	Critical Illness (Critically Ill) 02/2016
1	Multiple Organ Failure (MODS) 02/2016
1	Hypertension (High Blood Pressure) 06/2011
1	Bradycardia 06/2011
1	Experimental Arthritis 06/2011
1	Rheumatoid Arthritis 10/2009
1	Disease Progression 10/2009

Drug/Important Bio-Agent (IBA)

5	Kallikreins (Kallikrein)IBA 01/2021 - 01/2019
3	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2019
3	Pharmaceutical PreparationsIBA 01/2019 - 02/2016
3	Histamine Receptors (Histamine Receptor)IBA 11/2017 - 04/2011
3	Fingolimod Hydrochloride (FTY720)FDA Link 02/2016 - 06/2011
2	EnzymesIBA 01/2020 - 02/2016
2	quinolineIBA 11/2017 - 12/2016
2	Histamine H1 AntagonistsIBA 11/2017 - 05/2017
2	Kynurenine 3-Monooxygenase (Kynurenine 3 Monooxygenase)IBA 01/2017 - 01/2017
2	KynurenineIBA 01/2017 - 02/2016
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 01/2021
1	Serine Peptidase Inhibitor Kazal-Type 5IBA 01/2021
1	Co-Repressor ProteinsIBA 01/2021
1	Serum Amyloid P-ComponentIBA 01/2020
1	miridesapIBA 01/2020
1	AminopeptidasesIBA 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	SulfonamidesIBA 11/2017
1	SulfonesIBA 11/2017
1	AmidesIBA 05/2017
1	relaxin receptorsIBA 01/2017
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2017
1	Tryptophan (L-Tryptophan)FDA Link 02/2016
1	GSK180IBA 02/2016
1	compound 20IBA 06/2011
1	Histamine Antagonists (Antihistamines)IBA 04/2011
1	LigandsIBA 04/2011
1	CytokinesIBA 10/2009
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2009
1	Mitogen-Activated Protein Kinase 14IBA 10/2009

Therapy/Procedure

3	Intranasal Administration 11/2017 - 04/2011
1	Immunotherapy 01/2020
1	Therapeutics 02/2016